College of Agricultural Sciences

M. J. Reimers, Hahn, M. E., and Tanguay, R. L., “Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V alcohol dehydrogenase genes but have distinct functional characteristics.”, J Biol Chem, vol. 279, no. 37, pp. 38303-12, 2004.

S. K. Krueger, Siddens, L. K., Henderson, M. C., Andreasen, E. A., Tanguay, R. L., Pereira, C. B., Cabacungan, E. T., Hines, R. N., Ardlie, K. G., and Williams, D. E., “Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics.”, Pharmacogenet Genomics, vol. 15, no. 4, pp. 245-56, 2005.

N. Lassen, Estey, T., Tanguay, R. L., Pappa, A., Reimers, M. J., and Vasiliou, V., “Molecular cloning, baculovirus expression, and tissue distribution of the zebrafish aldehyde dehydrogenase 2.”, Drug Metab Dispos, vol. 33, no. 5, pp. 649-56, 2005.

B. R. Evans, Karchner, S. I., Allan, L. L., Pollenz, R. S., Tanguay, R. L., Jenny, M. J., Sherr, D. H., and Hahn, M. E., “Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear translocator.”, Mol Pharmacol, vol. 73, no. 2, pp. 387-98, 2008.

L. K. Mathew, Simonich, M. T., and Tanguay, R. L., “AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration.”, Biochem Pharmacol, vol. 77, no. 4, pp. 498-507, 2009.

W. H. Bisson, Koch, D. C., O'Donnell, E. F., Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S. Kumar, “Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.”, J Med Chem, vol. 52, no. 18, pp. 5635-41, 2009.

S. L. Harper, Carriere, J. Lee, Miller, J. M., Hutchison, J. Evan, Maddux, B. L. S., and Tanguay, R. L., “Systematic evaluation of nanomaterial toxicity: utility of standardized materials and rapid assays.”, ACS Nano, vol. 5, no. 6, pp. 4688-97, 2011.

S. Sengupta, Bisson, W. H., Mathew, L. K., Kolluri, S. K., and Tanguay, R. L., “Alternate glucocorticoid receptor ligand binding structures influence outcomes in an in vivo tissue regeneration model.”, Comp Biochem Physiol C Toxicol Pharmacol, vol. 156, no. 2, pp. 121-9, 2012.

E. F. O'Donnell, Kopparapu, P. Rao, Koch, D. C., Jang, H. Sang, Phillips, J. Lynne, Tanguay, R. L., Kerkvliet, N. I., and Kolluri, S. Kumar, “The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells.”, PLoS One, vol. 7, no. 7, p. e40926, 2012.

S. C. Tilton, Tal, T. L., Scroggins, S. M., Franzosa, J. A., Peterson, E. S., Tanguay, R. L., and Waters, K. M., “Bioinformatics Resource Manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools.”, BMC Bioinformatics, vol. 13, p. 311, 2012.

S. Lal, La Du, J., Tanguay, R. L., and Greenwood, J. A., “Calpain 2 is required for the invasion of glioblastoma cells in the zebrafish brain microenvironment.”, J Neurosci Res, vol. 90, no. 4, pp. 769-81, 2012.

T. L. Tal, Franzosa, J. A., Tilton, S. C., Philbrick, K. A., Iwaniec, U. T., Turner, R. T., Waters, K. M., and Tanguay, R. L., “MicroRNAs control neurobehavioral development and function in zebrafish.”, FASEB J, vol. 26, no. 4, pp. 1452-61, 2012.

T. L. Tal and Tanguay, R. L., “Non-coding RNAs--novel targets in neurotoxicity.”, Neurotoxicology, vol. 33, no. 3, pp. 530-44, 2012.

L. Truong, Saili, K. S., Miller, J. M., Hutchison, J. E., and Tanguay, R. L., “Persistent adult zebrafish behavioral deficits results from acute embryonic exposure to gold nanoparticles.”, Comp Biochem Physiol C Toxicol Pharmacol, vol. 155, no. 2, pp. 269-74, 2012.

J. S. Kirkwood, Lebold, K. M., Miranda, C. L., Wright, C. L., Miller, G. W., Tanguay, R. L., Barton, C. L., Traber, M. G., and Stevens, J. F., “Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.”, J Biol Chem, vol. 287, no. 6, pp. 3833-41, 2012.

G. W. Miller, Ulatowski, L., Labut, E. M., Lebold, K. M., Manor, D., Atkinson, J., Barton, C. L., Tanguay, R. L., and Traber, M. G., “The α-tocopherol transfer protein is essential for vertebrate embryogenesis.”, PLoS One, vol. 7, no. 10, p. e47402, 2012.

L. Truong, Reif, D. M., St Mary, L., Geier, M. C., Truong, H. D., and Tanguay, R. L., “Multidimensional in vivo hazard assessment using zebrafish.”, Toxicol Sci, vol. 137, no. 1, pp. 212-33, 2014.

I. Motorykin, Traber, M. G., Tanguay, R. L., and Maier, C. S., “Proteome-driven elucidation of adaptive responses to combined vitamin E and C deficiency in zebrafish.”, J Proteome Res, vol. 13, no. 3, pp. 1647-56, 2014.

P. Chatterjee, Padmanarayana, M., Abdullah, N., Holman, C. L., LaDu, J., Tanguay, R. L., and Johnson, C. P., “Otoferlin deficiency in zebrafish results in defects in balance and hearing: rescue of the balance and hearing phenotype with full-length and truncated forms of mouse otoferlin.”, Mol Cell Biol, vol. 35, no. 6, pp. 1043-54, 2015.

G. R. Garcia, Noyes, P. D., and Tanguay, R. L., “Advancements in zebrafish applications for 21st century toxicology.”, Pharmacol Ther, vol. 161, pp. 11-21, 2016.

A. Planchart, Mattingly, C. J., Allen, D., Ceger, P., Casey, W., Hinton, D., Kanungo, J., Kullman, S. W., Tal, T., Bondesson, M., Burgess, S. M., Sullivan, C., Kim, C., Behl, M., Padilla, S., Reif, D. M., Tanguay, R. L., and Hamm, J., “Advancing toxicology research using in vivo high throughput toxicology with small fish models.”, ALTEX, vol. 33, no. 4, pp. 435-452, 2016.

J. Chen, Wang, X., Ge, X., Wang, D., Wang, T., Zhang, L., Tanguay, R. L., Simonich, M. T., Huang, C., and Dong, Q., “Chronic perfluorooctanesulphonic acid (PFOS) exposure produces estrogenic effects in zebrafish.”, Environ Pollut, vol. 218, pp. 702-708, 2016.

J. G. Teeguarden, Tan, Y. - M., Edwards, S. W., Leonard, J. A., Anderson, K. A., Corley, R. A., Kile, M. L., Simonich, S. L. Massey, Stone, D., Tanguay, R. L., Waters, K. M., Harper, S. L., and Williams, D. E., “Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework.”, Environ Sci Technol, vol. 50, no. 9, pp. 4579-86, 2016.

B. Lemaire, Kubota, A., O'Meara, C. M., Lamb, D. C., Tanguay, R. L., Goldstone, J. V., and Stegeman, J. J., “Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders.”, Toxicol Appl Pharmacol, vol. 296, pp. 73-84, 2016.

L. Christine Wehmas, Tanguay, R. L., Punnoose, A., and Greenwood, J. A., “Developing a Novel Embryo-Larval Zebrafish Xenograft Assay to Prioritize Human Glioblastoma Therapeutics.”, Zebrafish, vol. 13, no. 4, pp. 317-29, 2016.